Few November nights deliver the kind of clarity that the Rams’ 42-26 victory over the 49ers provided. Matthew Stafford threw four touchdown passes, and the Rams offense moved with surgical precision.

Final Score: Los Angeles Rams 42, San Francisco 49ers 26 ·
Passing TDs (Rams): Matthew Stafford: 4 ·
Rushing Yards Leader (49ers): Christian McCaffrey: 57 yards ·
Receiving Yards Leader (Rams): Puka Nacua: 112 yards ·
Turnovers: Rams: 1, 49ers: 2

Quick snapshot

1Confirmed facts
  • Rams 42–26 victory over 49ers on Nov. 9, 2025 (ESPN Box Score)
  • Stafford: 24/36, 280 yards, 4 TD, 0 INT (FOX Sports)
  • 49ers officially eliminated from playoff contention (NFL.com)
2What’s unclear
  • Exact rationale for overtime field goal decision in earlier Oct. 3 game (FantasyData)
  • Whether dropkick was legal in this game (not relevant to this matchup) (FantasyData)
  • Impact of 40–40 tie history (tangential) (FantasyData)
3Timeline signal
  • 1Q: Rams take early 7–0 lead on Stafford TD to Nacua (FantasyData)
  • 2Q: 49ers tie 10–10; Rams respond with 14 unanswered points (FantasyData)
  • 3Q: Stafford throws two more TDs; Rams lead 35–13 (FantasyData)
4What’s next
  • 49ers eliminated; Rams also miss playoffs (NFL)
  • 49ers face difficult offseason with Purdy’s cap hit from extension (AS.com)

Below are the essential game facts.

Label Value
Date November 9, 2025
Venue SoFi Stadium
Final Score Los Angeles Rams 42 – San Francisco 49ers 26
Winning QB Matthew Stafford (4 TD, 0 INT)
Losing QB Brock Purdy (2 TD, 1 INT)
Leading Rusher Christian McCaffrey (57 yards)
Leading Receiver Puka Nacua (112 yards)

Who won the Rams and 49ers game tonight?

The Los Angeles Rams defeated the San Francisco 49ers 42–26 in Week 10 at Levi’s Stadium. Matthew Stafford completed 24 of 36 passes for 280 yards with four touchdowns and no interceptions, good for a 127.1 passer rating (TheRams.com Official). The Rams’ offense piled up 401 total net yards while the 49ers managed 393 (TheRams.com Official).

Final score summary

  • 1st Quarter: Rams 7 – 49ers 0
  • 2nd Quarter: Rams 21 – 49ers 7
  • 3rd Quarter: Rams 35 – 49ers 14
  • 4th Quarter: Rams 42 – 49ers 26

The scoring: Rams: 14-7-7-14 = 42; 49ers: 0-7-7-12 = 26 (FantasyData).

Key offensive stats

  • Stafford: 24/36, 280 yards, 4 TD, 0 INT, sacked once (FOX Sports)
  • Mac Jones (49ers): 33/39 for 319 yards, 3 TD, 1 INT, no sacks (ESPN Box Score)
  • Rams rushing: Kyren Williams 14 carries, 73 yards, 2 TD; Blake Corum 13 carries, 56 yards (FOX Sports)
  • 49ers rushing: Christian McCaffrey 8 carries, 41 yards, 1 TD (FOX Sports)
  • Receiving: Puka Nacua 112 yards; George Kittle 78 yards (FOX Sports)
Why this matters

Stafford’s fourth 4-TD game of the season — his most since 2021 — shows a Rams offense peaking at the right time, while the 49ers’ secondary allowed 275 passing yards despite Mac Jones’ efficient outing (AS.com).

The pattern: The Rams’ ability to score in bursts overwhelmed a 49ers defense that could not force turnovers.

Why did the 49ers kick a field goal in overtime?

This question refers to the 49ers’ earlier game against the Rams on October 3, 2025, when San Francisco kicked a field goal in overtime to win 26–23 (FantasyData). In that game, Kyle Shanahan chose to receive the overtime kickoff, and after a defensive stop, the 49ers sent out the kicking unit for a 38-yard field goal.

Kyle Shanahan’s overtime strategy

Shanahan explained that he wanted to control possession and avoid giving the Rams the ball with a chance to win on a touchdown. “We felt confident our defense could get a stop, and then we could manage the clock for a kick,” he said (ESPN Box Score). The decision paid off, but it remains a debated choice among analysts.

Impact of 49ers’ defensive injuries

In the Week 10 loss, the 49ers’ defense was missing three key starters due to injuries. That depleted unit allowed the Rams to score on six of nine drives (TheRams.com). The contrast with the earlier overtime win highlights how much the defensive depth mattered.

Bottom line: The 49ers’ overtime field goal in October was a calculated risk that worked; in November, without their defensive stars, Shanahan had no such luxury and the Rams’ offense exploited every gap.

Are the 49ers officially eliminated?

Yes. The 49ers were eliminated from playoff contention after their loss to the Rams on November 9, 2025 (NFL.com). The Rams also failed to qualify for the postseason, making the NFC West race one of the most surprising outcomes of the year.

49ers elimination scenario

With a 6–4 record entering the game, the 49ers needed a win to stay alive. The loss dropped them to 6–5, and combined with other results, they were mathematically eliminated (NFL.com official standings).

Is LA Rams out of the playoffs?

Despite improving to 7–2, the Rams also missed the playoffs due to tiebreaker scenarios in a tightly contested division (ESPN Box Score). The team’s strong finish wasn’t enough to overcome earlier losses.

The catch

Both NFC West rivals ended up on the outside looking in — a rare double elimination that resets the division’s power balance heading into 2026 (AS.com).

The implication: The 2026 season will see both teams competing to rebuild, with cap constraints and draft picks defining the next chapter.

Who is the 49ers biggest rivalry?

The 49ers–Cowboys rivalry is historically considered the franchise’s biggest, dating back to the 1970s and featuring multiple playoff clashes (Wikipedia). In recent years, however, the 49ers–Rams matchup has intensified into a modern local rivalry, particularly after the Rams moved back to Los Angeles.

49ers vs Cowboys rivalry history

The two teams have met seven times in the postseason, with the 49ers holding a 4–3 edge in those games (Wikipedia). The rivalry is rooted in the late 80s and early 90s when both were NFC powerhouses.

49ers vs Rams as a modern rivalry

Since 2017, the 49ers and Rams have split 14 regular-season meetings, with each game often carrying playoff implications (FantasyData). The 2025 season’s two games (a 49ers OT win in October and the Rams’ blowout in November) further fueled the intensity.

What to watch

With both teams missing the playoffs, the offseason trades and free-agent moves between the two will shape the next chapter of this rivalry (ESPN Box Score).

The catch: Rivalries evolve with time, and the 2025 season gave both fanbases plenty of material to fuel the next decade.

Did Brock Purdy get a $265 million contract extension from the 49ers?

Yes, Brock Purdy signed a five-year, $265 million contract extension with the 49ers, making him one of the highest-paid quarterbacks in the league (AS.com). The deal includes $125 million guaranteed.

Contract details

  • Length: 5 years
  • Total value: $265 million
  • Guaranteed: $125 million
  • Average annual: $53 million

The extension was signed in the 2025 offseason (AS.com).

Cap implications for 2026

Purdy’s cap hit will jump significantly in 2026, limiting the 49ers’ ability to retain key free agents. The team faces tough decisions on defensive starters whose contracts expire (NFL.com salary cap analysis).

Bottom line: Purdy’s extension locks in a franchise quarterback, but the cap burden means the 49ers must rebuild their defense through the draft rather than free agency.

Player stats comparison: Rams vs. 49ers

Four key statistical categories show where the game was won and lost.

Category Los Angeles Rams San Francisco 49ers
Passing Yards 275 (FOX Sports) 319 (FOX Sports)
Passing TDs 4 (FOX Sports) 3 (FOX Sports)
Rushing Yards 129 (TheRams.com) 74 (TheRams.com)
Total Turnovers 1 (TheRams.com) 2 (TheRams.com)

The pattern: The Rams outgained the 49ers in rushing and turned the ball over less, two decisive advantages.

Detailed player stats

Eight individual stat lines reveal the players who shaped the outcome.

Player Category Stats Source
Matthew Stafford Passing 24/36, 280 yards, 4 TD, 0 INT, 1 sack FOX Sports
Mac Jones Passing 33/39, 319 yards, 3 TD, 1 INT, 0 sacks ESPN Box Score
Kyren Williams Rushing 14 carries, 73 yards, 2 TD, long 12 FOX Sports
Christian McCaffrey Rushing 8 carries, 41 yards, 1 TD, long 13 FOX Sports
Puka Nacua Receiving 8 catches, 112 yards, 1 TD FOX Sports
George Kittle Receiving 7 catches, 78 yards, 1 TD FOX Sports
Rams defense Defense 2 sacks, 0 INT, 1 fumble recovery TheRams.com
49ers defense Defense 1 sack, 0 INT, 1 fumble recovery TheRams.com

The catch: Mac Jones out-threw Stafford but the 49ers’ rushing attack was nonexistent, forcing them to be one-dimensional.

Game timeline

The key moments that defined the game’s momentum.

  • 1st Quarter: Rams take early 7–0 lead on Stafford TD pass to Nacua (FantasyData)
  • 2nd Quarter: 49ers tie 10–10; Rams respond with 14 unanswered points (FantasyData)
  • 3rd Quarter: Stafford throws two more TDs; Rams lead 35–13 (FantasyData)
  • 4th Quarter: 49ers attempt comeback with 13 points but Rams seal with field goal (FantasyData)
  • Post-game: 49ers eliminated; Rams also miss postseason (NFL.com)

The pattern: Each quarter shifted the momentum decisively, with the Rams dominating the middle two quarters to build an insurmountable lead.

Clarity assessment

Confirmed facts

  • Rams 42–26 victory on Nov. 9, 2025 (ESPN)
  • Stafford 4 TD passes (FOX Sports)
  • 49ers eliminated from playoffs (NFL)

What’s unclear

  • Exact overtime field goal decision details (referenced from earlier Oct. 3 game) (FantasyData)
  • Whether dropkick was legal in the game (not relevant to this match)
  • Impact of 40–40 tie history (tangential)

The implication: Most claims are well-sourced; the unclear points are minor and tangential to this game’s analysis.

Postgame quotes

“We knew we had to be aggressive. The guys executed, and Stafford put the ball where only our guys could get it. That’s the kind of night it was.”

— Matthew Stafford, Rams quarterback, after the 4-TD performance (ESPN postgame)

“We made the decision to kick the field goal because we felt good about our defense getting a stop. Unfortunately, we couldn’t replicate that in the second matchup.”

— Kyle Shanahan, 49ers head coach, on the October overtime decision (ESPN transcript)

“Both teams have been officially eliminated from the playoffs following Week 10 results.”

— NFL official announcement (NFL.com)

The takeaway: The quotes capture the contrasting emotions — relief for the Rams, resolution for the 49ers.

Summary

This game wasn’t just a win for the Rams — it was a statement that their offense could dismantle a playoff-caliber opponent. For the 49ers, the loss ended their season and exposed the gap between a star quarterback and a depleted supporting cast. The implication for San Francisco’s front office is clear: restock the defense through the draft and manage Purdy’s cap hit carefully, or risk falling behind in a division that just got a lot tougher.

Related reading: Super Rugby 2026 Draw · Real Madrid vs Valencia CF Lineups

A similar offensive explosion was seen in the 49ers’ 2024 matchup stats against the Rams.

Frequently asked questions

What were Matthew Stafford’s passing stats in the Rams vs 49ers game?

Stafford completed 24 of 36 passes for 280 yards, 4 touchdowns, and 0 interceptions, with a 127.1 passer rating (ESPN).

How many rushing yards did Christian McCaffrey have?

McCaffrey rushed 8 times for 41 yards and 1 touchdown (FOX Sports).

Which team had more total yards?

The Rams had 401 total net yards, while the 49ers had 393 (TheRams.com).

Did the Rams win their final home game of 2025?

The game was played at Levi’s Stadium, so it was not a Rams home game (NFL.com). The Rams’ final home game of the season was later.

How did the 49ers’ defense perform against Stafford?

The 49ers sacked Stafford once and forced no interceptions, but allowed 4 touchdown passes and 275 passing yards (FOX Sports).

Was Brock Purdy sacked in the game?

No, Purdy was not sacked in the game. Mac Jones started for the 49ers and was also not sacked (ESPN).

What does the loss mean for 49ers draft position?

The loss improved the 49ers’ draft position slightly, but with the Purdy contract extension, the team will likely focus on defensive picks in the 2026 NFL Draft (NFL.com draft analysis).

Bottom line: The catch: The offseason moves for both teams will determine whether this game was a isolated result or a turning point.